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Symbioze®

Symbioze®

Symbioze®: fostering patient adherence with high-volume, multiple-use wearable

Symbioze^® is specifically tailored to administer complex drugs, such as biologic therapies, thanks to a highly engineered, reliable drug delivery system.
It is suitable for large volumes such as 20ml and beyond, while preserving the formulation integrity – which is critical especially with monoclonal antibodies.
It is designed to reconcile complex drugs injection with stakeholders’ (patients, HCP or payers) most demanding needs, with enough flexibility for adjustment to any pathology, targeted patient population and drug posology. Its reusable core technology can be re-used across multiple injections, leveraging its sustainable benefit for pharmaceutical players.

Patch-worn on-body injector
Reusable:
- Consists of drug-containing disposable element and reusable, rechargeable onboard electronic modules
- Locking system for safe assembly and disassembly of reusable and disposable parts
Ready to use:
- Prefilled and preloaded drug cartridge for patient’s safety
- Automatic soft canula insertion via needle safety system with hidden needle throughout the injection
- Innovative fluid path to maintain sterility from manufacturing to device use
Platform approach:
- Provides customization flexibility for adjustments to any pathology, targeted patient population and drug posology
- Can accommodate various drug volumes especially large-volume administration (20ml)
Connected:
- Drug recognition and verification via NFC communication
- Bluetooth built-in communication offers connectivity option

Sustainable and cost-effective
- Multiple-use of reusable electromechanical part with disposable drug-containing module
Intuitive and easy to use for optimum treatment adherence
- Simultaneous removal of ergonomic needle safety cap and adhesive liner, minimizing steps-of-use
- Provides live injection monitoring, audio-visual feedback, and failure mode control
- Enhanced treatment management with a broad range of connectivity features: treatment information, historical trending, infusion status, compliance…
- Easy pairing between device manager application with the core system
Ideal for complex, novel drugs administration whilst staying in line with pharma standards
- Enables large volume injection, with adjustable parameters (i.e: flowrate, viscosities, dose volume…)
- Specifically tailored for biologics to preserve formulation integrity
- Compatible with standard cartridges, filling and manufacturing processes

Our Parenteral featured services

Comprehensive tests range to ensure compliant and reliable drugdevice combination, leveraging know-how on standard deliverables including robustness study, device performances, pre-conditioning.

Diversified activities to evaluate the compatibility between device platform and specific selected primary drug containers, to ensure combination product performances and regulatory dossier filing.

Complete set of tests and evaluation to prove the biocompatibility of specific drug/device development process for regulatory dossier filing.