Developing inhalation devices with the patients, from early-stage to validation
Treating chronic respiratory diseases: a challenge for both patients and pharma providers.
Living with chronic respiratory diseases like Asthma ans COPD (Chronic Obstructive Pulmonary Disease) is more than a challenge, not only because these pathologies affect the airways, causing breathing difficulties, but also because the correct use of the device to administer the treatment is not always easy for them.
Global recommendations on the management of asthma2 and COPD3 highlight the importance of ensuring patients are adherent to their prescribed long term dosing regimen. However, adherence remains a big challenge which stems majorly from improper utilization of inhalation devices as well as lack of learning and training.
Several studies have shown that inhaler technique errors made by patients are common in real life with both pMDIs and DPIs despite advances in inhaler device technology. A synthesis of them gives the below split of inhalation technique observed in patients: 30% have a correct one, 40% have an acceptable one and 30% have a poor technic.
Training patients on the correct use of their inhaler can reduce the number of technique errors, but it may not be sufficient to solve the problem. Then, a better management of chronic respiratory therapies could be achieved by working on the inhalers ease of use or by giving real time feedback to the user on its technique to ensure more successful drug delivery.
Nemera understands the challenges encountered by patients living with chronic respiratory diseases and their difficulties of correctly using existing inhalers every day.
In order to design and develop a user-friendly and high-performing device, answering patients’ and technical needs, the only viable solution is to develop the device with the patients, from the early-stage phase to the final steps of validation. Patients’ opinions and feedback are crucial to ensure the best results on usability perspective, as they can offer ideas and inspiration based on their experience.
To read the full article: The PharmTech – Nemera_Human Factors in Inhalation
About the author:
Raphaële Audibert holds a biomedical engineering degree from ISIFC (Besançon, France). She has worked in the medical device industry as a project manager for five years, where she led the development of a surgical instrument set for neurosurgery. Ms Audibert joined Nemera in 2016 as Category Manager for Inhalation & Dermal. Since then, she has helped identify the needs of tomorrow and in building the franchise strategies.
Mark Tunkel was previously a partner at Insight Product Development, which was acquired by Nemera in 2019 and became the Insight Innovation Center. With more than 20 years of global business development experience and a deep understanding of the marketplace challenges and trends impacting the pharma industry, Mr. Tunkel has advised many of the world’s leading companies on their product development and innovation strategies, with an emphasis on driving realization and the most favorable business outcomes.
Manuela Basso is an experienced Communication professional, with a journalism and marketing background. She holds a European Master in Management with a specialization in International Marketing. With more than 10 years of marketing and communication experience in different fields, Ms. Basso has been working at Nemera for 6 years, developing effective communications to support Nemera’s overall vision and mission: to put patients first.
As a world-leading drug delivery device solutions provider, our purpose of putting patients first enables us to design and manufacture devices that maximize treatment efficacy. We are a holistic partner and help our customers succeed in the sprint to market of their combination products. From early device strategy to state-of-the-art manufacturing, we’re committed to the highest quality standards. Agile and open-minded, we work with our customers as colleagues. Together, we go the extra mile to fulfill our mission.
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